brain

We released the first comprehensive lipidomic atlas of the adult mouse brain on bioRxiv. Using MALDI mass spectrometry imaging, we mapped 172 membrane lipids across 109 sections and identified 539 spatially coherent biochemical domains we call lipizones.

Using a combination of sequencing techniques and mathematical methods, our lab has traced the genetic programs that direct the development of each cell in the brain. This molecular map help understanding how the brain develops and provide insights into a range of brain disorders. Nature paper here