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Over the last few days I have been at the École Polytechnique Fédérale de Lausanne (EPFL) Lausane, Switzerland. The reason of this little trip is that EPFL recently opened a special position at their School of Life Sciences….

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Congratulations to Lars and Simone! This week Simone Codelluppi and Lars Borm, in our lab have been releasing to the world their creation: osmFISH, a fantastic technique they have been optimizing to perfection! I really reccomand to read the preprint here

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Single-cell RNA-seq measurements provide a powerful approach for studying complex biological tissues. Some of the more interesting contexts involve dynamic processes, such as development or disease progression. However single-cell measurements only capture a snapshot of a transcriptional state at a single point in time.

Several approaches have been developed to infer dynamic processes, such as branching lineages, from this scRNA-seq. Usually those methods require …

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