lipidomics

We wrote a piece with Giovanni D’Angelo titled “The lipotype hypothesis” on Nature Reviews Molecular Cell Biology! Considering recent evidence on lipid-cell response to interaction cues, we proposed that cell variability in lipid composition assists the divergence of differentiation trajectories, leading to the establishment of several cell identities.

Using single-cell lipidomics our lab and the lab of Giovanni D’Angelo discovered the existence of lipotypes. Cell’s lipid composition can play a key role in determining what that cell will become. Science paper here

Using single-cell lipidomics our lab and the lab of Giovanni D’Angelo discovered the existence of lipotypes, cell states characterized by their lipid composition. We describe how lipid composition can play a key role in determining functional transitions. Science paper here