spatial

From cell “fat” to cell fate

Using single-cell lipidomics our lab and the lab of Giovanni D’Angelo discovered the existence of lipotypes, cell states characterized by their lipid composition. We describe how lipid composition can play a key role in determining functional transitions. Science paper here

“Molecular Tomographer” algorithm maps gene expression in space

Our lab has developed an algorithm that can work out the spatial pattern of gene expression inside the body without the need for microscopes and complicated equipment used currently. Nature Biotech paper here